The thyroid has a conspicuously distinctive architecture consisting of numerous follicles of various sizes, lined by cuboidal epithelium and filled with colloidal thyroglobulin. Thin supporting stroma of capillaries and connective tissue is inconspicuous between the follicles.
Calcitonin-secreting parafollicular cells (C cells) cannot be readily recognized on this specimen.
Variations in color-density of colloid, appearing here as ghostly bands extending horizontally across multiple follicles, represent "chatter," an artifact of sectioning.
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SIUC / School
of Medicine / Anatomy / David
Last updated: 28 October 2022 / dgk