Skin Biopsy Specimen
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Features which can be seen in this image include:
- Several small blood vessels, whose individual identities as venule, arteriole, or capillary are difficult to determine from this image. In any case a thin endothelial lining clearly distinguishes a vessel from a glandular duct.
- The blood vessels are associated with mild perivascular inflammatory infiltrate.
- "Perivascular" simply means "around the blood vessels". "Inflammatory infiltrate" consists of white blood cells which enter the tissue as part of the inflammatory response.
- Although it is not practical to identify reliably most individual cells in this region, the numerous small, roundish, intensely basophilic nuclei seen in this region are characteristic of lymphocytes.
- The inflammatory infiltrate is characterized as "mild" based on the relatively low numbers of white blood cells which appear here. This appearance should be contrasted with a more severe inflammatory infiltrate observable in other slides of inflamed tissue.
- Many small features (such as individual fibroblasts and collagen fibers) are not individually labelled.
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SIUC / School
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Last updated: 11 December 2007 / dgk