Endochondral bone formation occurs at the epiphyseal plate of a long bone. Click on the thumbnail at right for an overview.
As one scans across this image from left to right, one sees sequential stages in the process of endochondral ossification.
- Cartilage is growing (expanding) at the left.
- Across the middle of the image, we see progressive stages of:
- cartilage with hypertrophying chondrocytes (at left, pink with large lacunae),
- calcification of cartilage (deep purple),
- invasion of cartilage by bone (right, red).
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Last updated: 24 June 2022 / dgk