Esophagus, muscularis externa
The muscularis externa consists of skeletal muscle in the proximal (upper) third of the esophagus and smooth muscle in the distal third. This micrograph shows a transitional region in which both types of muscle are present.
The appearance, or visual texture, of muscle varies dramatically depending on the orientation of the fibers with respect to the plane of section. Most of the muscle fibers in this view are cut in cross section, but some smooth muscle fibers in the lower left corner are cut nearly longitudinally.
Individual smooth muscle fibers are usually difficult to resolve, especially at low magnification (as here). Cross-sectioned smooth muscle displays only scattered nuclei. In each individual fiber, the nucleus occupies only a small fraction of the fiber's length. So nuclei appear only in a similarly small proportion of the fibers cut by any single section. (Remember, each smooth muscle is a single cell, each with its own nucleus.)
Individual striated muscle fibers are conspicuous as individual units. Each fiber has so many nuclei that any random cross section typically displays at least one and often several, normally located around the periphery of the fiber.
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SIUC / School
of Medicine / Anatomy / David
Last updated: 9 May 2022 / dgk