Liver, cords and sinusoids, reticular fiber stain
Hepatocytes are arranged into cords, separated by vascular sinusoids lined by a fenestrated endothelium.
Beneath the endothelium (i.e., between the endothelium and the hepatocytes) is a narrow "space of Disse". Within this space of Disse are thin reticular fibers (a form of collagen) which provide support.
In this image, reticular fibers in the space of Disse are stained black with silver. Hepatocytes are faintly counterstained.
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Last updated: 14 May 2022 / dgk